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L-Se-methylselenocysteine(hencefore SMC)is a natural selenium-containing amino acid and a third-generation nutrient fortifier approved by China's CFDA and the U.S. FDA.

2024-11-11 11:06:22

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L-Se-methylselenocysteine(hencefore SMC)is a natural selenium-containing amino acid and a third-generation nutrient fortifier approved by China's CFDA and the U.S. FDA. It has various effects such as

L-Se-methylselenocysteine(hencefore SMC)is a natural selenium-containing amino acid and a third-generation nutrient fortifier approved by China's CFDA and the U.S. FDA. It has various effects such as tumor inhibition, antioxidant, assisting in the treatment of cardiovascular diseases, detoxification and detoxification. Because SMC can be decomposed into methylselenol directly under the action of β-cleaving enzyme in the human body, it is also called "methyl source selenium". In this article, we will analyze the importance of in future health research from the biological role of SMC, in order to deepden readers understanding of it.

                                                                                             

Anti-tumor  Anti-cancer

 

Studies have shown that the antitumor activity of Se is due to the production of methylselenium, which is produced by SMC through β-cleaving enzyme. Therefore, as one of the more chemically active selenium-containing compounds, SMC has good anticancer effects

 

Antioxidant Anti-aging

 

SMC is a scavenger of free radicals and functions directly as an antioxidant. It can prevent lipid peroxides from combining with free carboxyl groups, preventing free radicals from damaging related macromolecules on cell membranes, which in turn reduces the damage caused by free radicals and lipid peroxides to the organism, and plays a role in slowing down the aging process.SMC can also be indirectly involved in the antioxidant process by participating in the synthesis of peroxidases. It can enter the body as selenocysteine embedded in various selenium-containing proteins, and become the active center of antioxidant enzymes.

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Adjuvant therapy for cardiovascular

 

Selenium has strong antioxidant activity, which protects the integrity of cell membranes and enables cardiovascular cells to function normally. In coronary heart disease, atherosclerosis, hypertension and other cardiovascular diseases, free radicals, lipid peroxidation and LDL oxidative transformation play an important role.

 

Detoxification

 

SMC has the effect of detoxifying heavy metals because selenium has a strong affinity for metals and is a natural detoxifier against heavy metals. It combines with heavy metals in living organisms to form metal-selenium-protein complexes (complexes) that detoxify the metals.

 

 

 

参考:[1]R. Sinha, K. El-Bayoumy. Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds. Current Cancer Drug Targets, 2004, 4(1): 13-28

[2] H.J. Thompson, A.Wilson, J. Lu, M. Singh, C. Jiang, P. Upadhyaya, K. el-Bayoumy,C. Ip, Comparison of the effects of an organic and an inorganic form of selenium on amammary carcinoma cell line, Carcinogenesis 15 (1994) 183186.

[3]张俊杰.硒的生理功能及富硒强化食品的研究进展[J].微量元素与健康研究.2006,23(3):58-60.

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